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Molecular cloning and amino acid sequence of human 5-lipoxygenase.

5-Lipoxygenase (EC 1.13.11.34), a Ca2+-and ATP-requiring enzyme, catalyzes the first two steps in the biosynthesis of the peptidoleukotrienes and the chemotactic factor leukotriene B4. A cDNA clone corresponding to 5-lipoxygenase was isolated from a human lung lambda gt11 expression library by immun...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Matsumoto, T, Funk, C D, Rådmark, O, Höög, J O, Jörnvall, H, Samuelsson, B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829172/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.1.26
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