טוען...

Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase

[Image: see text] The melting curves of fatty acid amide hydrolase (FAAH) in the presence of 29 reversible inhibitors were measured using a thiol-reactive fluorophore. The thermal stability (T(m)) of the FAAH/inhibitor complex varied significantly depending on the chemical characteristics of the inh...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Slaymaker, Ian, Bracey, Michael, Mileni, Mauro, Garfunkle, Joie, Cravatt, Benjamin, Boger, Dale, Stevens, Raymond C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794692/
https://ncbi.nlm.nih.gov/pubmed/18644727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.06.086
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