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HTS-Compatible β-Lactamase Transcriptional Reporter Gene Assay for Interrogating the Heat Shock Response Pathway

Moderate environmental and physiological stressors are known to initiate protective heat shock response (HSR) leading to cell survival. HSR is largely mediated by the activation of heat shock factor (HSF), resulting in increased heat shock protein expression. Dysregulation of the HSR signaling has b...

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Autores principales: Hancock, Michael K, Xia, Menghang, Frey, Elizabeth S, Sakamuru, Srilatha, Bi, Kun
Formato: Artigo
Lenguaje:Inglês
Publicado: Bentham Open 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793398/
https://ncbi.nlm.nih.gov/pubmed/20161831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397300903010001
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