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Using β-lactamase and NanoLuc Luciferase Reporter Gene Assays to Identify Inhibitors of the HIF-1 Signaling Pathway

The hypoxia-inducible factor 1 (HIF-1) is a transcriptional factor involved in the regulation of oxygen within cellular environments. In hypoxic tissues or those with inadequate oxygen concentrations, activation of the HIF-1 transcription factor allows for subsequent activation of target gene expres...

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Foilsithe in:Methods Mol Biol
Main Authors: Khuc, Thai, Hsu, Chia-Wen (Amy), Sakamuru, Srilatha, Xia, Menghang
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375166/
https://ncbi.nlm.nih.gov/pubmed/27518620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6346-1_3
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