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Population pharmacokinetic analysis of varenicline in adult smokers
AIMS: To characterize the population pharmacokinetics of varenicline and identify factors leading to its exposure variability in adult smokers. METHODS: Data were pooled from nine clinical studies consisting of 1878 subjects. Models were developed to describe concentration–time profiles across indiv...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791973/ https://ncbi.nlm.nih.gov/pubmed/19916991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03520.x |
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