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Population pharmacokinetic analysis of carboxyhaemoglobin concentrations in adult cigarette smokers

AIMS: To develop a population-based model to describe and predict the pharmacokinetics of carboxyhaemoglobin (COHb) in adult smokers. METHODS: Data from smokers of different conventional cigarettes (CC) in three open-label, randomized studies were analysed using NONMEM (version V, Level 1.1). COHb c...

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Main Authors: Cronenberger, Carol, Mould, Diane R, Roethig, Hans-Juergen, Sarkar, Mohamadi
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291280/
https://ncbi.nlm.nih.gov/pubmed/17764477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02974.x
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