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Pharmacokinetic-Pharmacodynamic Modeling of the Effect of Varenicline on Nicotine Craving in Adult Smokers

INTRODUCTION: Varenicline has been shown to significantly reduce craving and several aspects of smoking reinforcement in clinical trials, compared with placebo. This is the first report describing the concentration-effect relationship of varenicline on relief of craving. METHODS: The pharmacokinetic...

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Detalhes bibliográficos
Publicado no:Nicotine Tob Res
Main Authors: Ravva, Patanjali, Gastonguay, Marc R., Faessel, Hélène M., Lee, Theodore C., Niaura, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832970/
https://ncbi.nlm.nih.gov/pubmed/25145377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntu154
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