Population pharmacokinetic analysis of varenicline in adult smokers

AIMS: To characterize the population pharmacokinetics of varenicline and identify factors leading to its exposure variability in adult smokers. METHODS: Data were pooled from nine clinical studies consisting of 1878 subjects. Models were developed to describe concentration–time profiles across indiv...

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Detaylı Bibliyografya
Asıl Yazarlar: Ravva, Patanjali, Gastonguay, Marc R, Tensfeldt, Thomas G, Faessel, Hélène M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2009
Konular:
Pharmacokinetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791973/
https://ncbi.nlm.nih.gov/pubmed/19916991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03520.x
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