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Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats

Glutamate transporters regulate synaptic concentrations of this neurotransmitter by coupling its flux to that of sodium and other cations. Available crystal structures of an archeal homologue of these transporters, GltPh, resemble an extracellular-facing state, in which the bound substrate is occlud...

詳細記述

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書誌詳細
主要な著者: Crisman, Thomas J., Qu, Shaogang, Kanner, Baruch I., Forrest, Lucy R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791632/
https://ncbi.nlm.nih.gov/pubmed/19926849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908570106
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