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Conserved Asparagine Residue Located in Binding Pocket Controls Cation Selectivity and Substrate Interactions in Neuronal Glutamate Transporter

Transporters of the major excitatory neurotransmitter glutamate play a crucial role in glutamatergic neurotransmission by removing their substrate from the synaptic cleft. The transport mechanism involves co-transport of glutamic acid with three Na(+) ions followed by countertransport of one K(+) io...

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Detalhes bibliográficos
Main Authors: Teichman, Shlomit, Qu, Shaogang, Kanner, Baruch I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366809/
https://ncbi.nlm.nih.gov/pubmed/22493292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355040
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