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A Conserved Methionine Residue Controls the Substrate Selectivity of a Neuronal Glutamate Transporter

Glutamate transporters located in the brain maintain low synaptic concentrations of the neurotransmitter by coupling its flux to that of sodium and other cations. In the binding pocket of the archeal homologue Glt(Ph), a conserved methionine residue has been implicated in the binding of the benzyl m...

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Bibliographic Details
Main Authors: Rosental, Noa, Kanner, Baruch I.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898430/
https://ncbi.nlm.nih.gov/pubmed/20424168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.087163
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