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Localization of PKA Phosphorylation Site, Serine-2030, in the Three-Dimensional Structure of Cardiac Ryanodine Receptor
Protein kinase A (PKA)-dependent phosphorylation of the cardiac Ca(2+) release channel/ryanodine receptor (RyR2) is believed to directly dissociate FKBP12.6 from the channel, causing abnormal channel activation and Ca(2+) release. To gain insight into the structural basis of the regulation of RyR2 b...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791347/ https://ncbi.nlm.nih.gov/pubmed/17967164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071257 |
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