Disease-causing Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator Determine the Functional Responses of Alveolar Macrophages

Alveolar macrophages (AMs) play a major role in host defense against microbial infections in the lung. To perform this function, these cells must ingest and destroy pathogens, generally in phagosomes, as well as secrete a number of products that signal other immune cells to respond. Recently, we dem...

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Detalhes bibliográficos
Principais autores: Deriy, Ludmila V., Gomez, Erwin A., Zhang, Guangping, Beacham, Daniel W., Hopson, Jessika A., Gallan, Alexander J., Shevchenko, Pavel D., Bindokas, Vytautas P., Nelson, Deborah J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791021/
https://ncbi.nlm.nih.gov/pubmed/19837664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057372
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