Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers

INTRODUCTION: Women who carry mutations in BRCA1 and BRCA2 have a substantially increased risk of developing breast cancer as compared with the general population. However, risk estimates range from 20 to 80%, suggesting the presence of genetic and/or environmental risk modifiers. Based on extensive...

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書誌詳細
主要な著者: Neuhausen, Susan L, Brummel, Sean, Ding, Yuan Chun, Singer, Christian F, Pfeiler, Georg, Lynch, Henry T, Nathanson, Katherine L, Rebbeck, Timothy R, Garber, Judy E, Couch, Fergus, Weitzel, Jeffrey, Narod, Steven A, Ganz, Patricia A, Daly, Mary B, Godwin, Andrew K, Isaacs, Claudine, Olopade, Olufunmilayo I, Tomlinson, Gail, Rubinstein, Wendy S, Tung, Nadine, Blum, Joanne L, Gillen, Daniel L
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
Research article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790858/
https://ncbi.nlm.nih.gov/pubmed/19843326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2414
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