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Quantifying Correlations Between Allosteric Sites in Thermodynamic Ensembles
Allostery describes altered protein function at one site due to a perturbation at another site. One mechanism of allostery involves correlated motions, which can occur even in the absence of substantial conformational change. We present a novel method, “MutInf”, to identify statistically significant...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790287/ https://ncbi.nlm.nih.gov/pubmed/20161451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct9001812 |
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