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A distinct subset of self-renewing human memory CD8(+) T cells survives cytotoxic chemotherapy

The mechanisms that maintain human T cell memory during normal and perturbed homeostasis are not fully understood. The repeated induction of profound lymphocytopenia in patients undergoing multiple cycles of cytotoxic chemotherapy infrequently results in severe infections with viruses controlled by...

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Detalhes bibliográficos
Main Authors: Turtle, Cameron J., Swanson, Hillary M., Fujii, Nobuharu, Estey, Elihu H., Riddell, Stanley R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789980/
https://ncbi.nlm.nih.gov/pubmed/19879163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.09.015
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