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Genetically retargeting CD8(+) lymphocyte subsets for cancer immunotherapy

The extraordinary sensitivity and specificity of T cells for their cognate antigen make them a highly attractive cancer therapeutic. However, the rarity of tumor-reactive T cells in cancer patients, the difficulty isolating them in sufficient numbers for adoptive immunotherapy, and the unpredictable...

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Detalhes bibliográficos
Main Authors: Turtle, Cameron J., Riddell, Stanley R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130496/
https://ncbi.nlm.nih.gov/pubmed/21237630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.12.012
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