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Genetically retargeting CD8(+) lymphocyte subsets for cancer immunotherapy
The extraordinary sensitivity and specificity of T cells for their cognate antigen make them a highly attractive cancer therapeutic. However, the rarity of tumor-reactive T cells in cancer patients, the difficulty isolating them in sufficient numbers for adoptive immunotherapy, and the unpredictable...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130496/ https://ncbi.nlm.nih.gov/pubmed/21237630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.12.012 |
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