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Immediate Cytotoxicity But Not Degranulation Distinguishes Effector and Memory Subsets of CD8(+) T Cells

CD8(+) T cells play a central role in the resolution and containment of viral infections. A key effector function of CD8(+) T cells is their cytolytic activity toward infected cells. Here, we studied the regulation of cytolytic activity in naive, effector, and central versus effector memory CD8(+) T...

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Detalhes bibliográficos
Main Authors: Wolint, Petra, Betts, Michael R., Koup, Richard A., Oxenius, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211884/
https://ncbi.nlm.nih.gov/pubmed/15051762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031799
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