Generation of CD19-chimeric antigen receptor modified CD8(+) T cells derived from virus-specific central memory T cells

The adoptive transfer of donor T cells that have been genetically modified to recognize leukemia could prevent or treat leukemia relapse after allogeneic HSCT (allo-HSCT). However, adoptive therapy after allo-HSCT should be performed with T cells that have a defined endogenous TCR specificity to avo...

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Bibliografiske detaljer
Main Authors: Terakura, Seitaro, Yamamoto, Tori N., Gardner, Rebecca A., Turtle, Cameron J., Jensen, Michael C., Riddell, Stanley R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251238/
https://ncbi.nlm.nih.gov/pubmed/22031866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-366419
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