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Synthesis of labeled meropenem for the analysis of M. tuberculosis transpeptidases
A concise synthesis of (14)C labeled meropenem prepared from (14)C dimethylamine hydrochloride is described. Using a similar reaction sequence, the meropenem nucleus was also attached to biotin providing a probe for protein interaction studies.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789577/ https://ncbi.nlm.nih.gov/pubmed/20161438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.10.124 |
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