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Meropenem-Clavulanic Acid Shows Activity against Mycobacterium tuberculosis In Vivo
The carbapenems imipenem and meropenem in combination with clavulanic acid reduced the bacterial burden in Mycobacterium tuberculosis-infected macrophages by 2 logs over 6 days. Despite poor stability in solution and a short half-life in rodents, treatment of chronically infected mice revealed signi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370771/ https://ncbi.nlm.nih.gov/pubmed/22450968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05690-11 |
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