Llwytho...
A single S phase double-strand break influences replicon dynamics and triggers a Mre11-Tel1/ATM-mediated mechanism controlling terminal fork integrity
Summary In response to replication stress, the Mec1/ATR and SUMO pathways control the stalled and damaged fork stability. We investigated the S phase response at forks encountering a broken template (termed terminal fork). We show that double strand break (DSB) formation can locally trigger dormant...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2009
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789576/ https://ncbi.nlm.nih.gov/pubmed/19361851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.02.016 |
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