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CD4(+) T Cell Development in a Mouse Expressing a Transgenic TCR Derived from a Regulatory T Cell
CD4(+)Foxp3(+) regulatory T cells (Tregs) maintain peripheral tolerance and influence immune responses to foreign antigens. The thymus is an important source of Tregs, but controversy exists as to whether T cells are selected into the Treg lineage based on signals received through TCRs specific for...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789337/ https://ncbi.nlm.nih.gov/pubmed/19065648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838772 |
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