Conventional and Regulatory CD4(+) T Cells That Share Identical TCRs Are Derived from Common Clones

Results from studies comparing the diversity and specificity of the TCR repertoires expressed by conventional (Tconv) and regulatory (Treg) CD4(+) T cell have varied depending on the experimental system employed. We developed a new model in which T cells express a single fixed TCRα chain, randomly r...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wolf, Kyle J., Emerson, Ryan O., Pingel, Jeanette, Buller, R. Mark, DiPaolo, Richard J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839724/
https://ncbi.nlm.nih.gov/pubmed/27100298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153705
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