Estrogen Receptor β protects against in vivo injury in RPE cells

Epidemiological data suggest that estrogen deficiency in post menopausal women may contribute to the severity of AMD. We discovered that 17β-estradiol (E(2)) was a crucial regulator of the severity of extracelllular matrix turnover (ECM) dysregulation both in vivo and in vitro. We also found in vitr...

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Detalhes bibliográficos
Main Authors: Elliot, Sharon J., Catanuto, Paola, Espinosa-Heidmann, Diego G., Fernandez, Pedro, Hernandez, Eleut, Saloupis, Peter, Korach, Kenneth, Karl, Michael, Cousins, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789169/
https://ncbi.nlm.nih.gov/pubmed/19799898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.09.001
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