Subtype Specific Estrogen Receptor Action Protects Against changes in MMP-2 Activation in Mouse Retinal Pigmented Epithelial Cells

Eyes with age-related macular degeneration (AMD) demonstrate accumulation of specific deposits and extracellular matrix (ECM) molecules under the retinal pigment epithelium (RPE). AMD is about two times more prevalent in aging postmenopausal women. Therefore we studied whether 17β-estradiol (E(2)) m...

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Main Authors: Elliot, Sharon, Catanuto, Paola, Fernandez, Pedro, Espinosa-Heidmann, Diego, Karl, Michael, Korach, Kenneth, Cousins, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409190/
https://ncbi.nlm.nih.gov/pubmed/18313050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.01.010
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