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Retinal Pigment Epithelium Protection From Oxidant-mediated Loss of MMP-2 Activation Requires Both MMP-14 and TIMP-2
PURPOSE: Eyes with age-related macular degeneration (AMD) demonstrate accumulation of specific deposits and extracellular matrix (ECM) molecules under the retinal pigment epithelium (RPE). Metalloproteinases (MMP) are crucial regulators of basement membrane and ECM turnover. Accordingly, loss of RPE...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1484406/ https://ncbi.nlm.nih.gov/pubmed/16565411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-1258 |
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