Testosterone and 17β-estradiol have opposite effects on podocyte apoptosis that precedes glomerulosclerosis in female estrogen receptor knockout mice

Podocyte damage and apoptosis are thought to be important if not essential in the development of glomerulosclerosis. Female estrogen receptor knockout mice develop glomerulosclerosis at 9 months of age due to excessive ovarian testosterone production and secretion. Here, we studied the pathogenesis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Doublier, Sophie, Lupia, Enrico, Catanuto, Paola, Periera-Simon, Simone, Xia, Xiaomei, Korach, Ken, Berho, Mariana, Elliot, Sharon J., Karl, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775100/
https://ncbi.nlm.nih.gov/pubmed/20962747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.398
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados