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Differential Effects of Continuous and Intermittent 17β-Estradiol Replacement and Tamoxifen Therapy on the Prevention of Glomerulosclerosis : Modulation of the Mesangial Cell Phenotype in Vivo
Female ROP Os/+ mice are partially protected by endogenous estrogens against progressive glomerulosclerosis (GS) during their reproductive period; however, ovariectomy accelerates GS progression. We examined the effects of continuous and intermittent 17β-estradiol (E(2)) replacement and tamoxifen th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698782/ https://ncbi.nlm.nih.gov/pubmed/16877338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051255 |
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