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DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa
DCP1 stimulates the decapping enzyme DCP2, which removes the mRNA 5′ cap structure committing mRNAs to degradation. In multicellular eukaryotes, DCP1-DCP2 interaction is stabilized by additional proteins, including EDC4. However, most information on DCP2 activation stems from studies in S. cerevisia...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789166/ https://ncbi.nlm.nih.gov/pubmed/19966221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909871106 |
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