Soluble state high resolution atomic force microscopy study of Alzheimer’s β-amyloid oligomers

We report here the direct observation of high resolution structures of assemblies of Alzheimer β-amyloid oligomers and monomers using liquid atomic force microscopy (AFM). Visualization of nanoscale features of Aβ oligomers (also known as ADDLs) was carried out in tapping mode AFM in F12 solution. O...

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Hauptverfasser: Shekhawat, Gajendra S., Lambert, Mary P., Sharma, Saurabh, Velasco, Pauline T., Viola, Kirsten L., Klein, William L., Dravid, Vinayak P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Institute of Physics 2009
Schlagworte:
Biophysics and Bio-Inspired Systems
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789110/
https://ncbi.nlm.nih.gov/pubmed/19997583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3251779
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