Soluble state high resolution atomic force microscopy study of Alzheimer’s β-amyloid oligomers

We report here the direct observation of high resolution structures of assemblies of Alzheimer β-amyloid oligomers and monomers using liquid atomic force microscopy (AFM). Visualization of nanoscale features of Aβ oligomers (also known as ADDLs) was carried out in tapping mode AFM in F12 solution. O...

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Hlavní autoři: Shekhawat, Gajendra S., Lambert, Mary P., Sharma, Saurabh, Velasco, Pauline T., Viola, Kirsten L., Klein, William L., Dravid, Vinayak P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Institute of Physics 2009
Témata:
Biophysics and Bio-Inspired Systems
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789110/
https://ncbi.nlm.nih.gov/pubmed/19997583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3251779
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