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Soluble state high resolution atomic force microscopy study of Alzheimer’s β-amyloid oligomers

We report here the direct observation of high resolution structures of assemblies of Alzheimer β-amyloid oligomers and monomers using liquid atomic force microscopy (AFM). Visualization of nanoscale features of Aβ oligomers (also known as ADDLs) was carried out in tapping mode AFM in F12 solution. O...

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Detalhes bibliográficos
Main Authors: Shekhawat, Gajendra S., Lambert, Mary P., Sharma, Saurabh, Velasco, Pauline T., Viola, Kirsten L., Klein, William L., Dravid, Vinayak P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Institute of Physics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789110/
https://ncbi.nlm.nih.gov/pubmed/19997583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3251779
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