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myo-Inositol Oxygenase: a Radical New Pathway for O(2) and C-H Activation at a Nonheme Diiron Cluster
The enzyme myo-inositol oxygenase (MIOX) catalyzes conversion of myo-inositol (cyclohexan-1,2,3,5/4,6-hexa-ol or MI) to D-glucuronate (DG), initiating the only known pathway in humans for catabolism of the carbon skeleton of cell-signaling inositol (poly)phosphates and phosphoinositides. Recent kine...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788986/ https://ncbi.nlm.nih.gov/pubmed/19173070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b811885j |
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