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An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn
The Cbl family of ubiquitin ligases function as negative regulators of activated receptor tyrosine kinases by facilitating their ubiquitination and subsequent lysosomal targeting. Here, we have investigated the role of Cbl ubiquitin ligase activity in the negative regulation of a non-receptor tyrosi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788922/ https://ncbi.nlm.nih.gov/pubmed/19966925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1615-4061(200205)2:1/2<29::AID-SITA29>3.0.CO;2-7 |
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