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An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn

The Cbl family of ubiquitin ligases function as negative regulators of activated receptor tyrosine kinases by facilitating their ubiquitination and subsequent lysosomal targeting. Here, we have investigated the role of Cbl ubiquitin ligase activity in the negative regulation of a non-receptor tyrosi...

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Main Authors: Rao, Navin, Ghosh, Amiya K., Douillard, Patrice, Andoniou, Christopher E., Zhou, Pengcheng, Band, Hamid
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788922/
https://ncbi.nlm.nih.gov/pubmed/19966925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1615-4061(200205)2:1/2<29::AID-SITA29>3.0.CO;2-7
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