TSC2 Deficiency Increases PTEN via HIF1α

Substantial evidence suggests roles of TSC2 and PTEN in the development of cancer predisposition syndromes. Loss of TSC2 results in benign tumors, neurological disorders, and angiomyolipomas. We found that PTEN mRNA and protein levels are elevated in Tsc2(−/−) mouse embryo fibroblasts with concomita...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Mahimainathan, Lenin, Ghosh-Choudhury, Nandini, Venkatesan, Balachandar, Das, Falguni, Mandal, Chandi C., Dey, Nirmalya, Habib, Samy L., Kasinath, Balakuntalam S., Abboud, Hanna E., Ghosh Choudhury, Goutam
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
主題:
Mechanisms of Signal Transduction
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788829/
https://ncbi.nlm.nih.gov/pubmed/19648120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028860
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍