MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes

Hyperglycemia induces a wide array of signaling pathways in the kidney that lead to hypertrophy and matrix expansion, eventually culminating in progressive kidney failure. High glucose-induced reduction of the tumor suppressor protein phosphatase and tensin homolog deleted in chromosome 10 (PTEN) co...

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Detalhes bibliográficos
Main Authors: Dey, Nirmalya, Das, Falguni, Mariappan, Meenalakshmi M., Mandal, Chandi Charan, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S., Choudhury, Goutam Ghosh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138272/
https://ncbi.nlm.nih.gov/pubmed/21613227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208066
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