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Betulinic Acid Derivatives as Human Immunodeficiency Virus Type 2 (HIV-2) Inhibitors

We previously reported that [[N-[3β-hydroxyl-lup-20(29)-en-28-oyl]-7-aminoheptyl]-carbamoyl]methane (A43D, 4) was a potent HIV-1 entry inhibitor. However, 4 was inactive against HIV-2 virus, suggesting the structural requirements for targeting these two retroviruses are different. In this study, a s...

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Bibliografische gegevens
Hoofdauteurs: Dang, Zhao, Lai, Weihong, Qian, Keduo, Ho, Phong, Lee, Kuo-Hsiung, Chen, Chin-Ho, Huang, Li
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788670/
https://ncbi.nlm.nih.gov/pubmed/19526990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9004253
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