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Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP(3) and PIP(2) in rabbit coronary artery myocytes

We investigate activation mechanisms of native TRPC1/C5/C6 channels (termed TRPC1 channels) by stimulation of endothelin-1 (ET-1) receptor subtypes in freshly dispersed rabbit coronary artery myocytes using single channel recording and immunoprecipitation techniques. ET-1 evoked non-selective cation...

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Detalhes bibliográficos
Main Authors: Saleh, Sohag N, Albert, Anthony P, Large, William A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788089/
https://ncbi.nlm.nih.gov/pubmed/19770190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.180331
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