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Thyroid hormone receptor (TR) mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire

Thyroid hormone receptors (TRs) are hormone-regulated transcription factors that control multiple aspects of normal physiology and development. Mutations in TRs have been identified at high frequency in certain cancers, including human hepatocellular carcinomas (HCCs). The majority of HCC TR mutants...

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Detalles Bibliográficos
Main Authors: Chan, Ivan H., Privalsky, Martin L.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787677/
https://ncbi.nlm.nih.gov/pubmed/19749797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.265
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