Thyroid hormone receptor (TR) mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire

Thyroid hormone receptors (TRs) are hormone-regulated transcription factors that control multiple aspects of normal physiology and development. Mutations in TRs have been identified at high frequency in certain cancers, including human hepatocellular carcinomas (HCCs). The majority of HCC TR mutants...

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Hlavní autoři: Chan, Ivan H., Privalsky, Martin L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787677/
https://ncbi.nlm.nih.gov/pubmed/19749797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.265
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