Loading...

Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation

Hematopoietic stem cells (HSCs) have a unique capacity to undergo self-renewal and multi-lineage differentiation to provide a lifetime supply of mature blood cells. By using conditional knockout technology, we disrupted the c-myb proto-oncogene specifically in adult bone marrow (BM) to demonstrate t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lieu, Yen K., Reddy, E. Premkumar
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787467/
https://ncbi.nlm.nih.gov/pubmed/19955420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907623106
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!