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Impaired adult myeloid progenitor CMP and GMP cell function in conditional c-myb-knockout mice

The differentiation of myeloid progenitors to mature, terminally differentiated cells is a highly regulated process. Here, we showed that conditional disruption of the c-myb proto-oncogene in adult mice resulted in dramatic reductions in CMP, GMP and MEP myeloid progenitors, leading to a reduction o...

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Hlavní autoři: Lieu, Yen K., Reddy, E. Premkumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466559/
https://ncbi.nlm.nih.gov/pubmed/22918254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21802
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