MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices

Complex signaling events control tumor invasion in three-dimensional (3D) extracellular matrices. Recent evidence suggests that cells utilize both matrix metalloproteinase (MMP)-dependent and MMP-independent means to traverse 3D matrices. Herein, we demonstrate that lysophosphatidic-acid-induced HT1...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Fisher, Kevin E., Sacharidou, Anastasia, Stratman, Amber N., Mayo, Anne M., Fisher, Sarah B., Mahan, Rachel D., Davis, Michael J., Davis, George E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Company of Biologists 2009
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787465/
https://ncbi.nlm.nih.gov/pubmed/19934222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.050724
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