Loading...

Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP–dependent proteolysis in 3-dimensional collagen matrices

Here we show that endothelial cells (EC) require matrix type 1-metalloproteinase (MT1-MMP) for the formation of lumens and tube networks in 3-dimensional (3D) collagen matrices. A fundamental consequence of EC lumen formation is the generation of vascular guidance tunnels within collagen matrices th...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Stratman, Amber N., Saunders, W. Brian, Sacharidou, Anastasia, Koh, Wonshill, Fisher, Kevin E., Zawieja, David C., Davis, Michael J., Davis, George E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714200/
https://ncbi.nlm.nih.gov/pubmed/19339693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-196451
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!