Structural Basis of the Interaction between Chemokine Stromal Cell-derived Factor-1/CXCL12 and Its G-protein-coupled Receptor CXCR4

The chemokine stromal cell-derived factor-1 (SDF-1/CXCL12) and its G-protein-coupled receptor (GPCR) CXCR4 play fundamental roles in many physiological processes, and CXCR4 is a drug target for various diseases such as cancer metastasis and human immunodeficiency virus, type 1, infection. However, a...

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מידע ביבליוגרפי
Main Authors: Kofuku, Yutaka, Yoshiura, Chie, Ueda, Takumi, Terasawa, Hiroaki, Hirai, Takahiro, Tominaga, Sae, Hirose, Masako, Maeda, Yoshitake, Takahashi, Hideo, Terashima, Yuya, Matsushima, Kouji, Shimada, Ichio
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2009
נושאים:
Protein Structure and Folding
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787383/
https://ncbi.nlm.nih.gov/pubmed/19837984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.024851
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