Carregant...

GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures

The 826 G protein-coupled receptors (GPCRs) in the human proteome regulate key physiological processes, and thus have long been attractive as drug targets. With crystal structure determinations of more than 50 different human GPCRs during the last decade, an initial platform for structure-based rati...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Rev Drug Discov
Autors principals: Shimada, Ichio, Ueda, Takumi, Kofuku, Yutaka, Eddy, Matthew T., Wüthrich, Kurt
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681916/
https://ncbi.nlm.nih.gov/pubmed/30410121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2018.180
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!