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Function-related conformational dynamics of G protein–coupled receptors revealed by NMR
G protein–coupled receptors (GPCRs) function as receptors for various neurotransmitters, hormones, cytokines, and metabolites. GPCR ligands impart differing degrees of signaling in the G protein and arrestin pathways, in phenomena called biased signaling, and each ligand for a given GPCR has a chara...
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| 發表在: | Biophys Rev |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer Berlin Heidelberg
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6557943/ https://ncbi.nlm.nih.gov/pubmed/31102199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-019-00539-w |
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