Function-related conformational dynamics of G protein–coupled receptors revealed by NMR

G protein–coupled receptors (GPCRs) function as receptors for various neurotransmitters, hormones, cytokines, and metabolites. GPCR ligands impart differing degrees of signaling in the G protein and arrestin pathways, in phenomena called biased signaling, and each ligand for a given GPCR has a chara...

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Bibliographic Details
Published in:Biophys Rev
Main Authors: Ueda, Takumi, Kofuku, Yutaka, Okude, Junya, Imai, Shunsuke, Shiraishi, Yutaro, Shimada, Ichio
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557943/
https://ncbi.nlm.nih.gov/pubmed/31102199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-019-00539-w
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