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Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments

C–C chemokine receptor 1 (CCR1) and CCR5 are involved in various inflammation and immune responses, and regulate the progression of the autoimmune diseases differently. However, the number of residues identified at the binding interface was not sufficient to clarify the differences in the CCR1- and...

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Bibliografiske detaljer
Udgivet i:J Biomol NMR
Main Authors: Yoshiura, Chie, Ueda, Takumi, Kofuku, Yutaka, Matsumoto, Masahiko, Okude, Junya, Kondo, Keita, Shiraishi, Yutaro, Shimada, Ichio
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662715/
https://ncbi.nlm.nih.gov/pubmed/26472202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-015-9992-x
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