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Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments

C–C chemokine receptor 1 (CCR1) and CCR5 are involved in various inflammation and immune responses, and regulate the progression of the autoimmune diseases differently. However, the number of residues identified at the binding interface was not sufficient to clarify the differences in the CCR1- and...

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Détails bibliographiques
Publié dans:J Biomol NMR
Auteurs principaux: Yoshiura, Chie, Ueda, Takumi, Kofuku, Yutaka, Matsumoto, Masahiko, Okude, Junya, Kondo, Keita, Shiraishi, Yutaro, Shimada, Ichio
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662715/
https://ncbi.nlm.nih.gov/pubmed/26472202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-015-9992-x
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