Dynamin 2 and c-Abl Are Novel Regulators of Hyperoxia-mediated NADPH Oxidase Activation and Reactive Oxygen Species Production in Caveolin-enriched Microdomains of the Endothelium

Reactive oxygen species (ROS) generation, particularly by the endothelial NADPH oxidase family of proteins, plays a major role in the pathophysiology associated with lung inflammation, ischemia/reperfusion injury, sepsis, hyperoxia, and ventilator-associated lung injury. We examined potential regula...

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Autori principali: Singleton, Patrick A., Pendyala, Srikanth, Gorshkova, Irina A., Mambetsariev, Nurbek, Moitra, Jaideep, Garcia, Joe G. N., Natarajan, Viswanathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Molecular Basis of Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787359/
https://ncbi.nlm.nih.gov/pubmed/19833721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013771
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